Study on the anti-microbial effect of Sinigrin against some pathogenic bacterial species

The increasing anti-bacterial drug resistance is one of the biggest challenges facing doctors around globe, so finding alternative treatments ideal options to overcome this problem. cruciferous family wealthiest plants worldwide because it contains most important secondary metabolites, glucosinolates, known for their anti-microbial properties. present study aimed evaluate effect glucosinolates (Sinigrin) against eight bacterial isolates (Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Actinomyces, Proteus mirabilis and Streptococcus pneumoniae). current investigated six concentrations pure Sinigrin (100, 300, 500, 700, 900, 1100 µg/ml). sensitivity various antibiotics was tested by VITIK 2DensiCheck equipment. activity assessed using agar diffusion method, microtiter plate method measured minimal inhibitory concentration (MIC). highest observed S. E. faecalis. started as lower 100 µg/ml, while a moderate seen P. aeruginosa K. pneumoniae at than 700 µg/ml. On other hand, not effective mirabilis, pneumoniae. It can be concluded from that has an on some bacteria which suggests possibility medicine in future. Keywords: Anti-bacterial activity, Agar well diffusion, Glucosinolates, Minimum inhibition antibiotic susceptibility, Sinigrin.